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(5E)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-1,3-thiazolidine-2,4-dione
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
(5E)-5-[(2,2-difluoro-1,3-benzodioxol-5‑yl)methylene]-1,3-thiazolidine‑2,4‑dione is a synthetic small molecule belonging to the thiazolidinedione class. It features a benzodioxole ring substituted with two fluorine atoms and is structurally related to other thiazolidinediones known for their insulin-sensitizing effects. This compound has been studied as an experimental agent and may act as an agonist of peroxisome proliferator–activated receptor gamma (PPARγ), similar to other drugs in its class. However, it does not have any approved medical indications or established clinical use as of now[1][6][7]. Its primary interest lies in research settings for potential metabolic or antidiabetic activity.
- Other names
- (5E)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-1,3-thiazolidine-2,4-dioneCHEMBL1231533CHEMBL-1231533CHEMBL 1231533ZINC000033821235ZINC-000033821235ZINC 000033821235
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)
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